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ea0026p232 | Pituitary | ECE2011

Copeptin in the differential diagnosis of the polydipsia–polyuria syndrome: revisiting the direct and indirect water deprivation tests

Fenske W K , Quinkler M , Haagen U , Papassotiriou J , Pfeiffer A F H , Fassnacht M , Stoerk S , Allolio B

Background: The water deprivation test (WDT) with direct or indirect measurement of plasma vasopressin (AVP) is the method of choice for the differential diagnosis of the polydipsia–polyuria syndrome. In theory, direct measurement of AVP is highly attractive but hampered by technical difficulties.Objective: To evaluate the utility of copeptin, a surrogate of AVP secretion, in the diagnostic work-up of the polyuria–polydipsia syndrome, and to co...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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